Thermo Fisher Scientific LASS6 Monoclonal Antibody (6B8)
LASS6 단백질을 인식하는 Mouse IgG2b monoclonal antibody로, Western blot 및 ELISA에 적합합니다. 인간과 랫트 반응성이 있으며, Affinity chromatography로 정제되었습니다. PBS buffer에 보존되며 연구용으로만 사용됩니다.
- 카탈로그번호
- H00253782-M02
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific LASS6 Monoclonal Antibody (6B8)
Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
ELISA
- Tested Dilution: 0.1 ng/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 6B8 |
| Immunogen | LASS6 (NP_982288, 62–131 a.a.) partial recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
PCAIALNIQA NGPQIAPPNA ILEKVFTAIT KHPDEKRLEG LSKQLDWDVR SIQRWFRQRR NQEKPSTLTR
Target Information
Longevity assurance genes (LAGs) represent a subgroup of the homeobox gene family. Five mammalian homologs have been reported, and the corresponding proteins have been investigated for their key role in ceramide synthesis. Members of the LAG family are also involved in cell growth regulation and cancer differentiation.
LASS6 may be involved in sphingolipid synthesis or its regulation. It interacts with ATP6V0C, ASGR1, ASGR2, and SLC22A1/OCT1. Localized to the nuclear membrane as a multi-pass membrane protein, it may also be expressed on the endoplasmic reticulum membrane. Glycosylation on Asn-18 is not necessary for function.
Like other LAG family members, the LASS6 protein contains a homeodomain and LAG1 domain and displays highest homology to LASS5. The corresponding gene is localized to human chromosome 2q24.3, spanning approximately 318 kb. Sequences in mouse and zebrafish suggest conservation of LASS6 in vertebrates. LASS6 is broadly expressed in various tissues and has been implicated in cancer differentiation and early embryonic development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 없음, OCR 텍스트만 통합됨)
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.