Thermo Fisher Scientific Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR) Monoclonal Antibody (LHCGR/7399)

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2, kappa

Class

Monoclonal

Type

Antibody

Clone

LHCGR/7399

Immunogen

Recombinant fragment (around aa 100-300) of human LHCGR protein. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:LHR,uniProtId:P22888-1,ncbiNodeId:9606,antigenRange:100-300,antigenLength:699,antigenImageFileName:3973-MSM9-P0_LHR_P22888-1_House_mouse.svg,antigenImageFileNamePDP:3973-MSM9-P0_LHR_P22888-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

200 µg/mL

Purification

Protein A/G

Storage buffer

PBS with 0.05% BSA

Contains

0.05% sodium azide

Storage conditions

4° C

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Positive Control:HepG2 or Jurkat cells. Human ovarian carcinoma.

Cellular Location: Cytoplasm. Cell surface.

Target Information

LHCGR encodes the receptor for both luteinizing hormone and choriogonadotropin. It is family 1 of G-protein coupled receptors, FSH/LSH/TSH superfamily, and its basic function is acting as luteinizing hormone/choriogonadotropin receptor (gonadotropin receptor). Regulating the development and function of Leyding cells in males. It also plays a role in male secondary sexual characterdevelopment. Mutations in this gonadotropinreceptor results in disorders of male secondary sexual characteristic development, such as familial male precocious puperty and male pseudohermaphtoditism.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.