
Thermo Fisher Scientific HER-2/c-erbB-2/neu/CD340 Recombinant Rabbit Monoclonal Antibody (ERBB2, 4376R)
HER2/ERBB2 단백질을 인식하는 Thermo Fisher recombinant rabbit monoclonal antibody입니다. IHC, ICC/IF, Flow Cytometry 등 다양한 응용에 최적화되어 있으며, 인간 시료 반응성이 확인되었습니다. 고순도 Protein A/G 정제, 무보존액 PBS 용액 형태로 제공됩니다.
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- 2064-RBM38-P1ABX
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Thermo Fisher Scientific HER-2/c-erbB-2/neu/CD340 Recombinant Rabbit Monoclonal Antibody (ERBB2, 4376R)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10^6 cells |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ERBB2, 4376R |
| Immunogen | Recombinant protein encoding the extracellular domain of human c-erbB2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Immunohistochemistry (PFA fixed): Incubate antibody for 30 minutes at room temperature.
Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA (pH 9.0) for 45 minutes at 95°C, followed by cooling at room temperature for 20 minutes.
Target Information
ErbB2 (HER2) is a receptor tyrosine kinase that is overexpressed in certain breast tumors.
Herceptin, used in treatment of metastatic HER2-positive cancer, is a monoclonal antibody targeting this kinase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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