
Thermo Fisher Scientific PDE10A Polyclonal Antibody
Rabbit polyclonal antibody against human PDE10A, validated for IHC (Paraffin) applications. Antigen affinity purified, unconjugated liquid form. Provides high specificity and stability with glycerol-based PBS buffer. For research use only.
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Applications
Tested Dilution
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PDE10A. Recombinant protein control fragment (Product #RP-90662) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2645322 |
Product Specific Information
Immunogen sequence:
TVEKWLKRKN NKSEDESAPK EVSRYQDTNM QGVVYELNSY IEQRLDTGGD NQLLLYELSS IIKIATKADG FALYFLGECN NSLCIFTPPG IKEGKPRLIP AGPITQGTTV SAYVAKSRKT LLVEDILGDE RFPRGTGLES GTRIQSVL
Antigen sequence identity:
- Mouse: 92%
- Rat: 94%
Target Information
Various cellular responses are regulated by the second messengers cAMP and cGMP. Phosphodiesterases, such as PDE10A, eliminate cAMP- and cGMP-mediated intracellular signaling by hydrolyzing the cyclic nucleotide to the corresponding nucleoside 5′-monophosphate.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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