Thermo Fisher Scientific PBK Polyclonal Antibody
Rabbit polyclonal antibody against human PBK (TOPK), suitable for WB, IHC, IP applications. Recognizes residues 200–250 of PBK. Supplied as unconjugated liquid at 1 mg/mL. Recommended storage at 4°C with 1-year shelf life.
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Applications
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 | |
| Immunohistochemistry (IHC) | 1:500–1:2,000 | |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:2,000 | |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 200 and 250 of human PDZ binding kinase (PBK) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
Target Information
PBK (TOPK) is a serine/threonine kinase related to dual specific mitogen-activated protein kinase (MAPKK). It is up-regulated in various hematological malignancies, participates in activation of lymphoid cells, and supports testicular function (spermatogenesis). Mitotic phosphorylation is required for its catalytic activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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