Thermo Fisher Scientific ATRX Recombinant Rabbit Monoclonal Antibody (HL1210)
ATRX 단백질을 표적으로 하는 Thermo Fisher Scientific의 재조합 토끼 단클론 항체 HL1210입니다. Western blot 및 면역세포화학(ICC/IF)에 사용 가능하며, HEK293 세포에서 발현된 IgG 형 항체입니다. 단백질 A로 정제되었으며 PBS 용액 형태로 제공됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | HL1210 |
| Immunogen | Recombinant protein encompassing a sequence within the C-terminus region of human ATRX (exact sequence proprietary) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.88 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C and avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2890279 |
Target Information
ATRX encodes a protein that contains an ATPase/helicase domain and belongs to the SWI/SNF family of chromatin remodeling proteins. Mutations in this gene are associated with X-linked mental retardation (XLMR) syndrome, often accompanied by alpha-thalassemia (ATRX) syndrome. These mutations can alter DNA methylation patterns, linking chromatin remodeling, DNA methylation, and gene expression in development. The protein undergoes cell cycle-dependent phosphorylation, regulating its nuclear matrix and chromatin association, suggesting roles in gene regulation during interphase and chromosomal segregation in mitosis. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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