Thermo Fisher Scientific IMPDH2 Recombinant Rabbit Monoclonal Antibody (23GB6670)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:5,000

-

Flow Cytometry (Flow)

1:2,000

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Expression System

HEK293F

Class

Recombinant Monoclonal

Type

Antibody

Clone

23GB6670

Immunogen

A synthesized peptide derived from human IMPDH2 (120-175AA). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:IMPDH2,uniProtId:P12268-1,ncbiNodeId:9606,antigenRange:120-175,antigenLength:514,antigenImageFileName:MA5-53090_IMPDH2_P12268-1_Rabbit.svg,antigenImageFileNamePDP:MA5-53090_IMPDH2_P12268-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Target Information

This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5-monophosphate into xanthine-5-monophosphate, which is then converted into guanosine-5`-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.