Thermo Fisher Scientific IRF4 Monoclonal Antibody (3A10)
IRF4 단백질을 인식하는 Mouse monoclonal antibody (Clone 3A10). Western blot과 ELISA에 적합하며, Human IRF4에 반응. PBS buffer, 무보존제, -20°C 보관. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
ELISA
- Tested Dilution: 0.03 ng/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3A10 |
| Immunogen | IRF4 (NP_002451, 342–451 a.a.) partial recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein Sequence:
LCNDRPNKLE RDQTCKLFDT QQFLSELQAF AHHGRSLPRF QVTLCFGEEF PDPQRQRKLI TAHVEPLLAR QLYYFAQQNS GHFLRGYDLP EHISNPEDYH RSIRHSSIQE
Target Information
The IRF (interferon regulatory factor) family of transcription factors are characterized by a unique tryptophan pentad repeat DNA-binding domain.
IRFs regulate interferons in response to viral infection and control interferon-inducible genes.
IRF4 is lymphocyte-specific and negatively regulates toll-like-receptor (TLR) signaling, essential for innate and adaptive immune activation.
A chromosomal translocation involving IRF4 and IgH locus, t(6;14)(p25;q32), may contribute to multiple myeloma.
Alternatively spliced transcript variants have been identified.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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