Thermo Fisher Scientific KAT5 Monoclonal Antibody (OTI6E1), TrueMAB
인간 KAT5(TIP60) 단백질을 인식하는 Mouse IgG1 단클론 항체. Western blot에 최적화된 TrueMAB 형식. 고순도 친화 크로마토그래피 정제 및 안정적 PBS/BSA/glycerol 저장 버퍼 구성. 연구용 DNA 손상 및 전사 조절 관련 연구에 적합.
- 카탈로그번호
- TA812334
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB)
Tested Dilution
- 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6E1 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 227–504 of human KAT5 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
TIP60 is a transcription factor originally isolated as an HIV-1 TAT-interactive protein, known to interact with the viral TAT protein that leads to HTATIP polyubiquitination and degradation. It belongs to the MYST family of histone acetyltransferases (HATs) and acts as a catalytic subunit of the NuA4 complex involved in transcriptional activation of select genes by acetylation of nucleosomal histone H4 and H2A. TIP60 functions as a co-regulator of transcription factors and can either promote or suppress tumorigenesis. It plays a crucial role in DNA repair, apoptosis, and signal transduction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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