Thermo Fisher Scientific KBTBD3 Polyclonal Antibody

Thermo Fisher Scientific KBTBD3 Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

• Recommended positive controls: PC-3
• Predicted reactivity: Mouse (89%), Rat (88%), Rhesus Monkey (99%)
• Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

The BTB (Broad-Complex, Tram track and Bric a brac) domain, also known as the POZ (Poxvirus and Zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers.
Proteins containing BTB domains are involved in transcriptional regulation via chromatin structure control.
KBTBD3 (Kelch repeat and BTB domain-containing protein 3), also known as BKLHD3, is a 608 amino acid protein with one BACK domain, one BTB (POZ) domain, and five kelch repeats.
The gene encoding KBTBD3 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome.
Defects in genes mapped to chromosome 11 are associated with Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema, and Smith-Lemli-Opitz syndrome.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

제품 이미지

(이미지 없음)