Thermo Fisher Scientific FAIM2 Polyclonal Antibody
FAIM2 단백질을 인식하는 Rabbit Polyclonal 항체로, 인간, 마우스, 랫트 시료에서 반응합니다. IHC, ICC/IF, ELISA에 적합하며, Protein A로 정제된 1 mg/mL 액상 제품입니다. 신경세포 사멸 억제 연구 및 LFG 단백질 분석에 활용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC-P) | Assay-dependent |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human FAIM2 (amino acids 211–316) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | –20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
LFG (Lifeguard) is a seven-transmembrane protein belonging to a family that inhibits apoptotic cell death induced by the Fas receptor. It is the human homolog of rat NMP35 and contains a conserved transmembrane domain and a small cytoplasmic domain. LFG protects cells from Fas-mediated neuronal apoptosis by binding to the Fas receptor without affecting Fas expression or FADD binding. It does not protect against TNF-alpha–mediated cell death. LFG is ubiquitously expressed, with higher expression in the hippocampus and other neural tissues, suggesting a neuroprotective role in neurodegenerative diseases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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