Thermo Fisher Scientific CD44v6 (Marker of Tumor Metastasis) Monoclonal Antibody (2F10)
CD44v6 종양 전이 표지 단백질을 인식하는 mouse monoclonal antibody. WB, IHC, ICC, Flow Cytometry 등 다양한 응용 가능. Recombinant human CD44 v9 domain 항원으로 제작. 고순도 Protein A/G 정제, 1 mg/mL 농도, PBS buffer 보존.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10^6 cells |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2F10 |
| Immunogen | Recombinant fragment corresponding to the v9 domain of human CD44 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
CD44 cell surface antigen is a 100 kDa glycoprotein widely expressed on human leukocytes, white matter of the brain, and by some epithelial cells of the intestine and breast. Several isoforms of CD44 exist, including the predominant CD44H isoform detected in many normal tissues.
CD44 acts as a receptor for hyaluronic acid (HA) and is involved in cell-cell interactions, adhesion, and migration. It also plays roles in lymphocyte activation, recirculation, and homing.
CD44 expression may be upregulated in certain carcinomas and is speculated to be associated with metastatic potential.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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