Thermo Fisher Scientific CHD1L Polyclonal Antibody
Rabbit polyclonal antibody against human CHD1L, validated for WB and IP applications. Targets residues 550–600 of CHD1L protein. Supplied as an unconjugated liquid at 0.20 mg/mL. Designed for chromatin relaxation and DNA damage response research.
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- pk
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Thermo Fisher Scientific CHD1L Polyclonal Antibody
Applications and Tested Dilution
- Western Blot (WB): 1:2,000–1:10,000
- Immunoprecipitation (IP): 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 550 and 600 of human Chromodomain Helicase DNA Binding Protein 1-Like |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
In response to DNA strand breaks, chromatin adopts a relaxed structure due to the addition of poly(ADP-ribose) (PAR) to chromatin proteins by PARP enzymes (see PARP1; MIM 173870). This relaxation facilitates the repair of DNA damage.
CHD1L interacts with PAR and plays a role in chromatin relaxation following DNA damage (Ahel et al., 2009 [PubMed 19661379]).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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