Thermo Fisher Scientific NOX3 Polyclonal Antibody
인간 NOX3 단백질을 인식하는 Rabbit Polyclonal 항체. Western blot 및 IHC(P) 실험에 적합. 합성 펩타이드 면역원으로 제작되어 높은 특이성과 재현성 제공. 내이 NOX3 관련 연구용으로 적합. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human NOX3 (Accession Q9HBY0), corresponding to amino acid residues Y127–G177 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2818602 |
Product Specific Information
Antibody detects endogenous levels of total NOX3.
Target Information
The NOX family of NADPH oxidases consists of seven transmembrane proteins that oxidize intracellular NADPH/NADH, facilitating electron transport across membranes and reducing molecular oxygen to superoxide.
NOX3 is predominantly expressed in the inner ear and is involved in the biogenesis of otoconia/otolith. It is suggested that NOX3 activation by Transient Receptor Potential Vanilloid 1 (TRPV1) increases reactive oxygen species levels in the inner ear, leading to STAT1-mediated inflammation and potential hearing loss.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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