Thermo Fisher Scientific TRBP1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:50

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human TRBP1. Recombinant protein control fragment (Product #RP-91765). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:TRBP1,uniProtId:Q13395-1,ncbiNodeId:9606,antigenRange:739-836,antigenLength:1621,antigenImageFileName:PA5-55130_TRBP1_Q13395-1_Rabbit.svg,antigenImageFileNamePDP:PA5-55130_TRBP1_Q13395-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.05 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2648892

Product Specific Information

Immunogen sequence: MNELNSVSDL DRCHLYLMVL TELINLHLKV GWKRGNPIWR VISLLKNASI QHLQEMDSGQ EPTVGSQIQR VVSMAALAMV CEAIDQKPEL QLDSLHAG

Highest antigen sequence identity to the following orthologs: Mouse - 64%, Rat - 59%.

Target Information

The human trans-activation response (TAR) RNA binding protein 1 (TRBP1) was initially identified as a protein that binds to the HIV-1 TAR RNA and activates the long terminal repeat (LTR) expression in the absence and presence of the viral trans-activator Tat. This binding is enhanced by the presence of co-factors such as elongation factor 1-a (EF-1-a), polypyrimidine tract-binding protein (PTB), and the chaperonin-like protein stimulator of TAR RNA-binding proteins (SRB). TRBP1 may act to disengage RNA polymerase II from TAR during transcriptional elongation if the RNA polymerase stalls at the TAR during transcriptional elongation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.