Thermo Fisher Scientific TRBP1 Polyclonal Antibody
인간 TRBP1 단백질을 표적으로 하는 Thermo Fisher Scientific의 토끼 폴리클론 항체입니다. 면역조직화학(IHC) 및 면역세포화학(ICC/IF)에 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용됩니다.
- 카탈로그번호
- PA555130
- 판매단위
- pk
카탈로그
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:20–1:50
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human TRBP1. Recombinant protein control fragment (Product #RP-91765) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2648892 |
Product Specific Information
Immunogen sequence:
MNELNSVSDL DRCHLYLMVL TELINLHLKV GWKRGNPIWR VISLLKNASI QHLQEMDSGQ EPTVGSQIQR VVSMAALAMV CEAIDQKPEL QLDSLHAG
- Highest antigen sequence identity to the following orthologs:
- Mouse: 64%
- Rat: 59%
Target Information
The human trans-activation response (TAR) RNA binding protein 1 (TRBP1) was initially identified as a protein that binds to the HIV-1 TAR RNA and activates the long terminal repeat (LTR) expression in the absence and presence of the viral trans-activator Tat. This binding is enhanced by co-factors such as elongation factor 1-a (EF-1-a), polypyrimidine tract-binding protein (PTB), and the chaperonin-like protein stimulator of TAR RNA-binding proteins (SRB).
TRBP1 may act to disengage RNA polymerase II from TAR during transcriptional elongation if the RNA polymerase stalls at the TAR during transcriptional elongation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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