Thermo Fisher Scientific MAPK13 Monoclonal Antibody (OTI12A11), TrueMAB
MAPK13 단백질을 인식하는 Mouse Monoclonal Antibody로, WB 및 ICC/IF에 적합. Human 시료 반응성. 고순도 Affinity chromatography 정제. 안정적인 액상 형태로 -20°C 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI12A11 |
| Immunogen | Full length human recombinant protein of human MAPK13 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
MAPK13 (p38 delta) is a serine/threonine kinase that transduces various extracellular signals, including cytokine and environmental stress responses. It regulates keratinocyte differentiation and is activated by environmental stresses and proinflammatory cytokines through phosphorylation by MAP kinase kinases or autophosphorylation via MAP3K7IP1/TAB1 interaction. Substrates include ATF2, MEF2C, MAX, CDC25B, and p53, indicating roles in stress-related transcription, cell cycle regulation, and genotoxic stress response. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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