
Thermo Fisher Scientific LOXL1 Polyclonal Antibody
Rabbit polyclonal antibody targeting human LOXL1 N-terminal region. Validated for Western blot at 0.2–1 µg/mL. Purified by affinity chromatography, supplied in PBS with sucrose and sodium azide. For research use only.
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Applications
- Western Blot (WB): 0.2–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal of human LOXL1 (aa 38–87) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2608049 |
Product Specific Information
Peptide sequence:
RWRQLIQWEN NGQVYSLLNS GSEYVPAGPQ RSESSSRVLL AGAPQAQQRRSequence homology:
Cow: 83%
Guinea Pig: 100%
Horse: 92%
Human: 100%
Mouse: 100%
Rabbit: 86%
Rat: 100%
Target Information
This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyzes the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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