Thermo Fisher Scientific IL24 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.5-3 µg/mL

-

Flow Cytometry (Flow)

2-5 µg per million cells

-

Product Specifications

Species Reactivity

Human, Non-human primate

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

udSynthetic peptide corresponding to aa 123-136 of human IL-24. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:IL24,uniProtId:Q13007-1,ncbiNodeId:9606,antigenRange:123-136,antigenLength:206,antigenImageFileName:PA1-41066_IL24_Q13007-1_Rabbit.svg,antigenImageFileNamePDP:PA1-41066_IL24_Q13007-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Protein G

Storage buffer

PBS with 0.2% gelatin

Contains

0.05% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2124791

Product Specific Information

Suggested positive control: Jurkat, antigen standard for IL24 (transient overexpression lysate), Jurkat whole cell lysate.

Target Information

Interleukin 24 (IL-24)/melanoma differentiation-associated gene-7 (mda-7) encodes a secreted protein that exhibits significant homology to the interleukin 10 (IL-10) family of cytokines. The human IL-24 is secreted by activated peripheral blood mononuclear cells and binds two heterodimeric receptors, IL-22R1/IL-20R2 and IL-20R1/IL-20R2 resulting in the activation of JAK/STAT signaling pathways. Mda-7/IL-24, selectively induces growth suppression, apoptosis and radiosensitization in malignant gliomas in a p53-independent manner.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.