Thermo Fisher Scientific Arylsulfatase G Polyclonal Antibody
Human Arylsulfatase G 단백질을 인식하는 Rabbit Polyclonal Antibody. IHC(P)에서 1:200~1:500 희석으로 검증됨. 항원 친화 크로마토그래피로 정제된 액상 항체로, 4°C 단기 보관 및 -20°C 장기 보관 권장. 연구용으로만 사용 가능.
- 카탈로그번호
- PA554729
- 판매단위
- pk
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Applications
Immunohistochemistry (Paraffin) [IHC (P)]
- Tested Dilution: 1:200–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human Arylsulfatase G. Recombinant protein control fragment (Product # RP-93287) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2638259 |
Product Specific Information
Immunogen sequence:
YVTGIIGKWH LGHHGSYHPN FRGFDYYFGI PYSHDMGCTD TPGYNHPPCP ACPQGDGPSR NLQRDCYTDV ALPLYENLNI VEQPV
- Highest antigen sequence identity to the following orthologs:
- Mouse: 88%
- Rat: 87%
Target Information
Sulfatases, such as ARSG, hydrolyze sulfate esters from sulfated steroids, carbohydrates, proteoglycans, and glycolipids. They are involved in hormone biosynthesis, modulation of cell signaling, and degradation of macromolecules.
This gene, a novel arylsulfatase, has activity toward pseudosubstrates including p-nitrocatechol sulfate and 4-methylumbelliferyl sulfate. Activity is competitively inhibited by phosphate.
The unprocessed protein is active as a 63-kDa monomer and demonstrates an acidic pH optimum as typically seen for lysosomal sulfatases.
The protein accumulates within lysosomes and is also a glycoprotein that binds specifically to mannose 6-phosphate receptors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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