Thermo Fisher Scientific Myoferlin Polyclonal Antibody
Rabbit polyclonal antibody targeting human Myoferlin (residues 700–750). Validated for Western blot and immunoprecipitation. Supplied as liquid, 1 mg/mL concentration. Recommended storage at 4°C with 1-year shelf life. For research use only.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 700–750 of human Myoferlin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from the date of receipt.
Target Information
Mutations in dysferlin, a protein associated with the plasma membrane, can cause muscle weakness that affects both proximal and distal muscles. The protein encoded by this gene is a type II membrane protein structurally similar to dysferlin. It belongs to the ferlin family and associates with both plasma and nuclear membranes. The protein contains C2 domains involved in calcium-mediated membrane fusion events, suggesting a role in membrane regeneration and repair. Two transcript variants encoding different isoforms have been identified, and additional variants may exist but have not been fully characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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