Thermo Fisher Scientific ESRRA Monoclonal Antibody (OTI2H9), TrueMAB
인간 ESRRA 단백질을 타깃으로 하는 Mouse IgG1 단클론 항체로 Western Blot에 최적화. 고순도 친화 크로마토그래피 정제, 액상 형태로 1 mg/mL 농도. 안정적 PBS/BSA/glycerol 버퍼로 구성되어 연구용으로 적합.
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Applications
- Western Blot (WB)
Tested Dilution
- 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2H9 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 206–417 of human ESRRA produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Estrogen-related receptor alpha 1 (ERRα, ERR1) is an orphan member of the nuclear hormone receptor superfamily. All ERR family members share an almost identical DNA-binding domain, showing 68% amino acid identity with that of the estrogen receptor. ERRα binds to an ERR-alpha response element (ERRE) containing a single consensus half-site (5'-tnaaggtca-3') and can interact with the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1, acting as an important regulator of the MCAD promoter. Studies indicate that ERR1 functions as a metabolic regulator and is highly expressed in tissues that preferentially metabolize fatty acids. The corresponding gene for ERR1 is NR3B1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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