
Thermo Fisher Scientific MAPK13 Monoclonal Antibody (OTI2A10), TrueMAB
MAPK13 단백질을 인식하는 Mouse Monoclonal Antibody로 Western blot, IHC, ICC/IF에 적합. 인간 시료 반응성, 고순도 Affinity chromatography 정제. Lyophilized 형태로 안정적이며, 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:4,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2A10 |
| Immunogen | Full length human recombinant protein of human MAPK13 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
MAPK13 (p38 delta) is a serine/threonine kinase involved in transducing extracellular signals such as cytokine and environmental stress responses. It regulates keratinocyte differentiation and is activated through phosphorylation by MAP kinase kinases or autophosphorylation via MAP3K7IP1/TAB1 interaction.
Substrates include ATF2, MEF2C, MAX, CDC25B, and p53, indicating roles in transcription regulation, cell cycle control, and genotoxic stress response.
Four alternatively spliced transcript variants encoding distinct isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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