
Thermo Fisher Scientific VPS4B Polyclonal Antibody
VPS4B 단백질을 인식하는 토끼 폴리클로날 항체로, Western blot에 적합합니다. Human, Mouse, Rat 시료에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태로 제공되며, 장기 보관 시 -20°C에서 보관합니다.
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Applications
- Western Blot (WB): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues in Human VPS4B |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2719673 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is greater than 95% as determined by SDS-PAGE.
Target Information
The VPS4B protein belongs to the AAA protein family (ATPases associated with diverse cellular activities) and is homologous to the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified, sharing high amino acid sequence similarity with each other, yeast Vps4, and mouse Skd1 proteins. Mouse Skd1 (suppressor of K⁺ transport defect 1) is a yeast Vps4 ortholog. Functional studies indicate that both human paralogs associate with endosomal compartments and are involved in intracellular protein trafficking, similar to Vps4 in yeast. The gene encoding this paralog is located on chromosome 18, while the other paralog resides on chromosome 16.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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