
ELK Biotechnology SIGL9 rabbit pAb
SIGL9 rabbit pAb는 인간, 쥐, 생쥐에 반응하는 폴리클로날 항체로, WB와 ELISA에 적합합니다. 인간 단백질 유래 펩타이드(AA 10-90)를 면역원으로 하며, 50kD 밴드 검출에 사용됩니다. -20°C에서 1년 보관 가능하며, IgG 아이소타입을 갖습니다.
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제품명
SIGL9 rabbit pAb
적용 분야
- WB
- ELISA
권장 희석 배율
- WB: 1:500–2000
- ELISA: 1:5000–20000
제품 정보
| 항목 | 내용 |
|---|---|
| Immunogen | Synthesized peptide derived from human protein (AA range: 10–90) |
| Species Reactivity | Human; Rat; Mouse |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 50 kD |
| GeneID (Human) | 27180 |
| Human Swiss-Prot No | Q9Y336 |
| Cellular Localization | Membrane; Single-pass type I membrane protein |
| Storage | -20°C / 1 year |
Background
Contains one copy of a cytoplasmic motif referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM), involved in modulation of cellular responses. The phosphorylated ITIM motif can bind the SH2 domain of several SH2-containing phosphatases.
Putative adhesion molecule mediating sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- or alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.
Online information: Siglec-9
Similarity: Belongs to the immunoglobulin superfamily; SIGLEC (sialic acid binding Ig-like lectin) family. Contains 1 Ig-like V-type domain and 2 Ig-like C2-type domains.
Tissue specificity: Expressed by peripheral blood leukocytes (neutrophils and monocytes but not eosinophils). Found in liver, fetal liver, bone marrow, placenta, spleen, and lower levels in various tissues including skeletal muscle, fetal brain, stomach, lung, thymus, prostate, brain, mammary gland, adrenal gland, colon, trachea, cerebellum, testis, small intestine, and spinal cord.
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