ELK Biotechnology TLR9 rabbit pAb
TLR9 단백질을 인식하는 토끼 폴리클로날 항체로, WB 및 ELISA에 사용 가능. 인간 및 생쥐 시료에 반응하며, 세포 내 TLR9 발현 연구에 적합. -20°C에서 1년 보관 가능.
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다ELK Biotechnology · ELK Biotechnology TLR9 rabbit pAb
제품명
TLR9 rabbit pAb
제품 설명
TLR9 단백질을 인식하는 토끼 유래 폴리클로날 항체입니다. 병원체 인식 및 선천 면역 활성화 연구에 활용되며, Western blot(WB) 및 ELISA 분석에 적합합니다.
제품 특성
| 항목 | 내용 |
|---|---|
| Applications | WB, ELISA |
| Recommended Dilutions | WB 1:500–1:2000, ELISA 1:5000–1:20000 |
| Immunogen | Synthesized peptide derived from human protein (AA range: 400–480) |
| Host | Rabbit |
| Storage | -20°C, 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 113 kDa |
| Gene ID (Human) | 54106 |
| Human Swiss-Prot No. | Q9NR96 |
| Species Reactivity | Human, Mouse |
| Cellular Localization | Endoplasmic reticulum membrane; Single-pass type I membrane protein; Endosome; Lysosome; Cytoplasmic vesicle (phagosome). Relocalizes from ER to endosome and lysosome upon stimulation with agonist. Exit from ER requires UNC93B1. Endolysosomal localization is essential for proteolytic cleavage and activation. Intracellular localization helps prevent response to self nucleic acid. |
Background
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) expressed on infectious agents and mediate cytokine production necessary for effective immunity. TLR9 is preferentially expressed in immune cell–rich tissues such as spleen, lymph node, bone marrow, and peripheral blood leukocytes. Studies in mice and humans indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response. (RefSeq, Jul 2008)
ELK Biotechnology 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.