ELK Biotechnology TRML1 rabbit pAb
TRML1 단백질을 인식하는 토끼 폴리클로날 항체로, WB와 ELISA에 적합합니다. 인간 및 생쥐 시료 반응성이 있으며, 세포막 및 세포질 단백질 분석에 활용됩니다. -20°C에서 1년 보관 가능합니다.
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제품명
TRML1 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Applications | WB; ELISA |
| Recommended Dilutions | WB: 1:500–2000 ELISA: 1:5000–20000 |
| Immunogen | Synthesized peptide derived from human protein (AA range: 30–110) |
| Host | Rabbit |
| Storage | -20°C, 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 34 kDa |
| Gene ID (Human) | 340205 |
| Human Swiss-Prot No. | Q86YW5 |
| Species Reactivity | Human; Mouse |
세포 내 위치 (Cellular Localization)
Cell membrane; Single-pass type I membrane protein. Cytoplasm. Sequestered in cytoplasmic vesicles in resting platelets (PubMed:15100151). Transported to the cell surface after stimulation by thrombin (PubMed:15100151). Soluble fragments can be released into the serum by proteolysis (PubMed:16505478).
배경 (Background)
This gene encodes a member of the triggering receptor expressed on myeloid cells-like (TREM) family. The encoded protein is a type I single Ig domain orphan receptor localized to the alpha-granule membranes of platelets. It is involved in platelet aggregation, inflammation, and cellular activation, and has been linked to Gray platelet syndrome. Alternative splicing results in multiple transcript variants (RefSeq, Nov 2012).
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