ELK Biotechnology NADL2 rabbit pAb
인간, 생쥐, 랫드에서 반응하는 NADL2 rabbit polyclonal antibody입니다. WB와 ELISA에 사용 가능하며, 고순도 IgG 형태로 1 mg/ml 농도 제공. 합성 펩타이드 면역원 기반으로 제작되어 안정적인 신호 검출에 적합합니다.
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제품명
NADL2 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Applications | WB; ELISA |
| Recommended Dilutions | WB 1:500–2000, ELISA 1:5000–20000 |
| Immunogen | Synthesized peptide derived from human protein (AA range: 190–270) |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 87 kD |
| GeneID (Human) | 254827 |
| Human Swiss-Prot No. | Q58DX5 |
| Cellular Localization | Membrane; Single-pass type II membrane protein |
| Species Reactivity | Human; Rat; Mouse |
| Storage | -20°C / 1 year |
Background
Although related to the peptidase M28 family, NADL2 is probably inactive as a hydrolase due to lack of the conserved zinc-binding and active sites.
May be catalytically inactive.
The gene maps to 3q26.31, a region associated with Cornelia de Lange syndrome; however, PubMed:15168106 failed to identify specific mutations in a panel of DNA samples from patients with Cornelia de Lange syndrome.
Sequence caution: Contaminating sequence at the C-terminus.
Similarity: Belongs to the peptidase M28 family, M28B subfamily.
Tissue specificity: Expressed at higher levels in kidney and placenta. In embryo, mainly confined to duodenal and stomach endoderm, mesonephros, metanephros, and pancreas.
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