ELK Biotechnology HBA rabbit pAb
HBA 단백질을 인식하는 토끼 폴리클로날 항체로, WB와 ELISA에 적합합니다. 합성 펩타이드를 면역원으로 하며, 사람·쥐·생쥐 시료에 반응합니다. -20°C에서 1년 보관 가능하며, 1 mg/ml 농도로 제공됩니다.
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ELK Biotechnology HBA rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | HBA rabbit pAb |
| Applications | WB; ELISA |
| Recommended Dilutions | WB 1:500–2000, ELISA 1:5000–20000 |
| Immunogen | Synthesized peptide derived from human protein (AA range: 30–110) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 15 kDa |
| GeneID (Human) | 3039 |
| Human Swiss-Prot No. | P69905 |
| Cellular Localization | Extracellular region, cytosol, hemoglobin complex, membrane, cytosolic small ribosomal subunit, haptoglobin-hemoglobin complex, extracellular exosome, endocytic vesicle lumen, blood microparticle |
| Species Reactivity | Human; Rat; Mouse |
Background
The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5′- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3′. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5′ untranslated regions and the introns, but they differ significantly over the 3′ untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported. [provided by RefSeq, Jul 2008]
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