
ELK Biotechnology TRY2 rabbit pAb
Human, Rat, Mouse에 반응하는 TRY2 rabbit polyclonal antibody로 WB 및 ELISA에 적합. 인간 단백질 유래 합성 펩타이드 면역원 사용. 27kD 밴드 관찰, 고순도 IgG 형태. -20°C에서 1년 보관 가능.
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제품명
TRY2 rabbit pAb
제품 개요
ELK Biotechnology에서 제공하는 TRY2 rabbit polyclonal antibody는 인간 단백질 유래 합성 펩타이드를 면역원으로 제작된 항체로, WB 및 ELISA 분석에 적합합니다. 이 항체는 trypsin family serine protease에 속하는 anionic trypsinogen을 인식하며, 다양한 종(인간, 생쥐, 랫트)에 반응합니다.
제품 스펙
| 항목 | 내용 |
|---|---|
| Applications | WB; ELISA |
| Recommended Dilutions | WB 1:500–2000, ELISA 1:5000–20000 |
| Immunogen | Synthesized peptide derived from human protein (AA range: 40–120) |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 27 kD |
| GeneID (Human) | 5645 |
| Human Swiss-Prot No | P07478 |
| Cellular Localization | Secreted, extracellular space |
| Species Reactivity | Human; Rat; Mouse |
| Storage | -20°C, 1 year |
Background
This gene belongs to the trypsin family of serine proteases and encodes anionic trypsinogen. It is part of a cluster of trypsinogen genes located within the T cell receptor beta locus. Enzymes of this family cleave peptide bonds that follow lysine or arginine residues. This protein is highly expressed in pancreatic juice, and its upregulation is characteristic of pancreatitis. It also activates pro-urokinase in ovarian tumors, suggesting a role in tumor invasion. Additionally, it cleaves across the type II collagen triple helix in rheumatoid arthritis synovitis tissue, potentially contributing to cartilage matrix degradation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
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