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ELK Biotechnology R4RL2 rabbit pAb
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ELK Biotechnology R4RL2 rabbit pAb

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R4RL2 rabbit polyclonal antibody for WB and ELISA applications. Recognizes human, rat, and mouse proteins. Targets a peptide from human protein (AA 290–370). Suitable for neuronal surface localization studies. Stable for 1 year at -20°C.

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pk
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ELK Biotechnology ES11214-100UL R4RL2 rabbit pAb, 100UL pk판매 단위 pk ·
재고 확인 필요
402,000원VAT 포함 442,200원
ELK Biotechnology ES11214-50UL R4RL2 rabbit pAb, 50UL pk판매 단위 pk ·
재고 확인 필요
301,000원VAT 포함 331,100원

ELK Biotechnology · ELK Biotechnology R4RL2 rabbit pAb

제품명

R4RL2 rabbit pAb

공급업체

ELK Biotechnology

제품 개요

R4RL2 rabbit polyclonal antibody는 인간 단백질 유래 합성 펩타이드(AA 290–370)를 면역원으로 제작된 항체로, 신경세포 표면 및 축삭 부위에서의 단백질 발현 연구에 적합합니다. WB 및 ELISA 실험에 활용 가능하며, 다양한 종에 반응성을 보입니다.

제품 스펙

항목 내용
Applications WB; ELISA
Recommended Dilutions WB 1:500–2000, ELISA 1:5000–20000
Immunogen Synthesized peptide derived from human protein (AA range: 290–370)
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band 46 kD
GeneID (Human) 349667
Human Swiss-Prot No Q86UN3
Species Reactivity Human; Rat; Mouse
Storage -20°C / 1 year

세포 내 위치

Cell membrane; Lipid-anchor, GPI-anchor; Membrane raft; Cell projection (dendrite, axon); Perikaryon. Localized to the surface of neurons, including axons. Detected close to synapses, but excluded from synapses.

배경 정보

  • Function: May play a role in regulating axonal regeneration and plasticity in the adult central nervous system.
  • Post-translational modification (PTM): Undergoes zinc metalloproteinase-mediated ectodomain shedding in neuroblastoma cells; BRE is released as a full-length ectodomain and an N-terminal fragment containing the LRR region.
  • Similarity: Belongs to the Nogo receptor family; contains 8 leucine-rich repeat (LRR) motifs.
  • Subcellular location: Localized to the surface of neurons, including axons.
  • Tissue specificity: Highly expressed in brain and liver; lower expression in kidney, mammary gland, placenta, skeletal muscle, spleen, and thyroid.

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