ELK Biotechnology STAB2 rabbit pAb
STAB2 단백질을 인식하는 토끼 폴리클로날 항체로 IHC 및 IF에 사용 가능. 인간, 랫드, 마우스에 반응하며 세포막 및 세포질에 위치. 고순도의 IgG 항체로 -20°C에서 1년 보관 가능.
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STAB2 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | STAB2 rabbit pAb |
| Applications | IHC; IF |
| Recommended Dilutions | IHC-p 1:50–300, IF 1:100–300 (다른 응용은 아직 테스트되지 않음) |
| Immunogen | Synthesized peptide derived from human protein (AA range: 980–1060) |
| Host | Rabbit |
| Storage | -20°C, 1년 보관 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 280 kDa |
| Gene ID (Human) | 55576 |
| Human Swiss-Prot No. | Q8WWQ8 |
| Cellular Localization | Cell membrane; Single-pass type I membrane protein; Cytoplasm. Only a small amount appears to be present at the cell surface (PubMed:17145755). |
| Species Reactivity | Human; Rat; Mouse |
Background
This gene encodes a large transmembrane receptor protein that may function in angiogenesis, lymphocyte homing, cell adhesion, or receptor scavenging. The protein contains 7 fasciclin, 15 epidermal growth factor (EGF)-like, and 2 laminin-type EGF-like domains as well as a C-type lectin-like hyaluronan-binding Link module. It is primarily expressed on sinusoidal endothelial cells of the liver, spleen, and lymph node. The receptor binds and endocytoses ligands such as hyaluronan, low-density lipoprotein, Gram-positive and Gram-negative bacteria, and advanced glycosylation end products. Supporting its possible role as a scavenger receptor, the protein cycles between the plasma membrane and lysosomes. [provided by RefSeq, Jul 2008]
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