ELK Biotechnology BEX3 rabbit pAb

제품명

BEX3 rabbit pAb

공급업체

ELK Biotechnology

제품 설명

BEX3 rabbit polyclonal antibody는 인간, 랫드, 마우스 시료에서 BEX3 단백질을 검출하기 위해 제작된 항체입니다. 이 항체는 세포 내 핵과 세포질에 존재하는 BEX3 단백질을 인식하며, WB 및 ELISA 분석에 적합합니다.

제품 스펙

Background

• Domain: Nuclear export signal required for export from nucleus and interactions with itself and p75NTR/NGFR.
• Function: May act as a signaling adapter molecule involved in p75NTR-mediated apoptosis induced by NGF. Plays a role in zinc-triggered neuronal death (By similarity).
• Miscellaneous: Binds transition metals.
• PTM: Ubiquitinated; degraded by proteasome.
• Similarity: Belongs to the BEX family.
• Subcellular Location: Shuttles between cytoplasm and nucleus; associates with replicating mitochondria.
• Subunit: Self-associates; interacts with 14-3-3 epsilon (YWHAE), DIABLO/SMAC (By similarity), and binds DEATH domain of p75NTR/NGFR.
• Tissue Specificity: Found in ovarian granulosa cells, testis, prostate, and seminal vesicle tissue. High levels also detected in liver.

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