ELK Biotechnology FKBP5 rabbit pAb
FKBP5 단백질을 인식하는 토끼 폴리클로날 항체로, WB와 ELISA에 적합합니다. 인간 및 생쥐 시료에 반응하며, 세포질과 핵에서 발현되는 단백질 검출에 사용됩니다. 고순도 IgG 형태로 -20°C에서 1년 보관 가능합니다.
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FKBP5 Rabbit Polyclonal Antibody
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | FKBP5 rabbit pAb |
| Applications | WB; ELISA |
| Recommended Dilutions | WB 1:500–1:2000, ELISA 1:5000–1:20000 |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 50 kDa |
| Gene ID (Human) | 2289 |
| Human Swiss-Prot No. | Q13451 |
| Cellular Localization | Cytoplasm, Nucleus |
| Species Reactivity | Human, Mouse |
Background
The protein encoded by this gene is a member of the immunophilin protein family, which plays a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin, and is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has multiple polyadenylation sites, and alternative splicing results in multiple transcript variants.
[provided by RefSeq, Mar 2009]
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