ELK Biotechnology PORIM rabbit pAb
PORIM rabbit pAb는 인간, 쥐, 랫트 시료에 반응하는 다클론 항체로 WB 및 ELISA에 적합합니다. 세포막 단백질 PORIM을 인식하며, 세포사멸 관련 연구에 활용됩니다. -20°C에서 1년간 보관 가능합니다.
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제품명
PORIM rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Applications | WB; ELISA |
| Recommended Dilutions | WB 1:500–2000, ELISA 1:5000–20000 |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 22 kD |
| Gene ID (Human) | 114908 |
| Human Swiss-Prot No | Q8N131 |
| Cellular Localization | Membrane; Single-pass type I membrane protein |
| Species Reactivity | Human; Rat; Mouse |
Background
This gene encodes a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti-PORIMIN (pro-oncosis receptor inducing membrane injury) antibody crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. This gene product is proposed to function as a cell surface receptor that mediates cell death.
[provided by RefSeq, Jul 2008]
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