ELK Biotechnology ANX13 rabbit pAb
Human 및 Mouse 시료에 반응하는 ANX13 rabbit polyclonal antibody로, WB와 ELISA에 적합합니다. 합성 펩타이드 유래 면역원 사용, 고순도 IgG 형태, 1 mg/ml 농도로 제공되며 -20°C에서 1년간 안정적으로 보관 가능합니다.
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제품명
ANX13 rabbit pAb
주요 정보
| 항목 | 내용 |
|---|---|
| Applications | WB; ELISA |
| Recommended Dilutions | WB: 1:500–2000, ELISA: 1:5000–20000 |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Species Reactivity | Human; Mouse |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 34 kD |
| GeneID (Human) | 312 |
| Human Swiss-Prot No | P27216 |
| Storage | -20°C / 1 year |
| Host | Rabbit |
세포 내 위치 (Cellular Localization)
Apical cell membrane, cell membrane (lipid-anchor), cytoplasmic vesicle.
Myristoylation anchors the protein to the membrane, but the protein also displays calcium-dependent, reversible binding to lipid membranes (PubMed:30610115).
Associated with the plasma membrane of undifferentiated, proliferating crypt epithelial cells as well as differentiated villus enterocytes (PubMed:1530946).
Background
This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways.
The specific function of this gene has not yet been determined; however, it is associated with the plasma membrane of undifferentiated, proliferating endothelial cells and differentiated villus enterocytes.
Alternatively spliced transcript variants encoding different isoforms have been identified.
[provided by RefSeq, Jul 2008]
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