ELK Biotechnology PON3 rabbit pAb
PON3 rabbit polyclonal antibody for WB and ELISA applications. Recognizes human, rat, and mouse proteins. Targets secreted PON3 involved in lipid metabolism and atherosclerosis. High specificity and stable storage at -20°C for up to one year.
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ELK Biotechnology PON3 rabbit pAb
제품 개요
PON3 rabbit polyclonal antibody는 인간, 랫, 마우스 시료에서 PON3 단백질을 검출하기 위한 항체입니다. PON3는 HDL과 결합하여 LDL 산화를 억제하는 효소로, 동맥경화 진행을 늦추는 기능을 가집니다.
제품 스펙
| 항목 | 내용 |
|---|---|
| Product name | PON3 rabbit pAb |
| Applications | WB; ELISA |
| Recommended Dilutions | WB 1:500–2000, ELISA 1:5000–20000 |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Species Reactivity | Human; Rat; Mouse |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 38 kD |
| GeneID (Human) | 5446 |
| Human Swiss-Prot No | Q15166 |
| Cellular Localization | Secreted, extracellular space |
| Storage | -20°C / 1 year |
| Host | Rabbit |
Background
This gene is a member of the paraoxonase family and lies in a cluster on chromosome 7 with the other two family members. The encoded protein is secreted into the bloodstream and associates with high-density lipoprotein (HDL). The protein also rapidly hydrolyzes lactones and can inhibit the oxidation of low-density lipoprotein (LDL), a function that is believed to slow the initiation and progression of atherosclerosis. Alternatively spliced variants which encode different protein isoforms have been described; however, only one has been fully characterized. (provided by RefSeq, Jul 2008)
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