ELK Biotechnology NEUS rabbit pAb
NEUS rabbit pAb는 인간, 랫트, 마우스에서 반응하는 다클론 항체로 WB 및 ELISA에 적합합니다. 합성 펩타이드 유래 면역원으로 제작되었으며, 신경 세포 성장 조절 관련 단백질 검출에 유용합니다. -20°C에서 1년간 안정적으로 보관 가능합니다.
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제품명
NEUS rabbit pAb
응용 분야
- Western Blot (WB)
- ELISA
권장 희석 배율
- WB: 1:500–2000
- ELISA: 1:5000–20000
제품 정보
| 항목 | 내용 |
|---|---|
| Immunogen | Synthesized peptide derived from part region of human protein |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 45 kD |
| Gene ID (Human) | 5274 |
| Human Swiss-Prot No | Q99574 |
| Cellular Localization | Secreted; Cytoplasmic vesicle, secretory vesicle lumen; Perikaryon |
| Species Reactivity | Human, Rat, Mouse |
배경
This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The protein is primarily secreted by axons in the brain and preferentially reacts with and inhibits tissue-type plasminogen activator. It is thought to play a role in the regulation of axonal growth and the development of synaptic plasticity. Mutations in this gene result in familial encephalopathy with neuroserpin inclusion bodies (FENIB), which is a dominantly inherited form of familial encephalopathy and epilepsy characterized by the accumulation of mutant neuroserpin polymers. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
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