ELK Biotechnology HRG rabbit pAb
HRG 단백질을 인식하는 토끼 폴리클로날 항체로 WB 및 ELISA에 적합. 합성 펩타이드 면역원 기반으로 제작되었으며, 인간·쥐·마우스 시료에 반응. 1 mg/ml 농도, -20°C에서 1년 보관 가능.
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ELK Biotechnology HRG rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | HRG rabbit pAb |
| Applications | WB; ELISA |
| Recommended Dilutions | WB 1:500–2000, ELISA 1:5000–20000 |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 57 kD |
| GeneID (Human) | 3273 |
| Human Swiss-Prot No | P04196 |
| Cellular Localization | Secreted |
| Species Reactivity | Human; Rat; Mouse |
Background
This histidine-rich glycoprotein contains two cystatin-like domains and is located in plasma and platelets. The physiological function has not been determined but it is known that the protein binds heme, dyes, and divalent metal ions. The encoded protein also has a peptide that displays antimicrobial activity against C. albicans, E. coli, S. aureus, P. aeruginosa, and E. faecalis. It can inhibit rosette formation and interacts with heparin, thrombospondin, and plasminogen. Two of the protein’s effects—the inhibition of fibrinolysis and the reduction of inhibition of coagulation—indicate a potential prothrombotic effect. Mutations in this gene lead to thrombophilia due to abnormal histidine-rich glycoprotein levels. [Provided by RefSeq, Nov 2014]
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