ELK Biotechnology CYTS rabbit pAb
CYTS rabbit pAb는 사람, 쥐, 생쥐 시료에 반응하는 폴리클로날 항체입니다. WB와 ELISA에 적합하며, 합성 펩타이드 면역원으로 제작되었습니다. -20°C에서 1년 보관 가능하며, 15kD 밴드를 검출합니다. Cystatin 단백질 연구에 유용합니다.
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ELK Biotechnology CYTS rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | CYTS rabbit pAb |
| Applications | WB; ELISA |
| Recommended Dilutions | WB 1:500–2000, ELISA 1:5000–20000 |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 15 kD |
| Gene ID (Human) | 1472 |
| Human Swiss-Prot No | P01036 |
| Cellular Localization | Secreted |
| Species Reactivity | Human; Rat; Mouse |
Background
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins, and the kininogens.
The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes.
This gene is located in the cystatin locus and encodes a type 2 salivary cysteine peptidase inhibitor. The protein is an S-type cystatin, based on its high level of expression in saliva, tears, and seminal plasma. The specific role in these fluids is unclear but antibacterial and antiviral activity is present, consistent with its biological function.
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