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ELK Biotechnology IL18 rabbit pAb
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IL18 rabbit polyclonal antibody for WB, IF, and ELISA applications. Derived from human peptide, detects 21kD band. Suitable for human, rat, and mouse samples. Stable for 1 year at -20°C.
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- pk
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ELK Biotechnology ES10872-100UL IL18 rabbit pAb, 100UL pk판매 단위 pk ·
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402,000원VAT 포함 442,200원
ELK Biotechnology ES10872-50UL IL18 rabbit pAb, 50UL pk판매 단위 pk ·
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301,000원VAT 포함 331,100원
ELK Biotechnology · ELK Biotechnology IL18 rabbit pAb
제품명
IL18 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Applications | WB, IF, ELISA |
| Recommended Dilutions | WB 1:500–2000; IF 1:100–300; ELISA 1:5000–20000 (Not yet tested in other applications) |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 21 kD |
| GeneID (Human) | 3606 |
| Human Swiss-Prot No | Q14116 |
| Cellular Localization | Cytoplasm, Secreted. The precursor is cytosolic (PubMed:33883744). In response to inflammasome-activating signals, cleaved and secreted (PubMed:33883744). Mature form is secreted and released in the extracellular milieu via the gasdermin-D (GSDMD) pore (PubMed:33883744). The precursor form is retained due to an acidic region removed by CASP1 during maturation (PubMed:33883744). Secretion depends on protein unfolding and is facilitated by TMED10 (PubMed:32272059). |
| Background | The IL18 gene encodes a proinflammatory cytokine that enhances natural killer cell activity in spleen cells and stimulates interferon-gamma production in T-helper type I cells. Alternatively spliced transcript variants encoding different isoforms have been identified (RefSeq, Aug 2011). |
| Species Reactivity | Human, Rat, Mouse |
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