ELK Biotechnology CEAM6 rabbit pAb
CEAM6 단백질을 인식하는 토끼 폴리클로날 항체로 WB 및 ELISA에 사용 가능. 인간, 랫트, 마우스 시료에 반응. 세포막에 위치한 GPI-앵커 단백질 검출에 적합. 종양 표지자 및 세포 접착 관련 연구에 활용.
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ELK Biotechnology CEAM6 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product Name | CEAM6 rabbit pAb |
| Applications | WB; ELISA |
| Recommended Dilutions | WB 1:500–2000, ELISA 1:5000–20000 |
| Immunogen | Synthesized peptide derived from part region of human protein (AA range: 100–150) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 37 kD |
| GeneID (Human) | 4680 |
| Human Swiss-Prot No | P40199 |
| Cellular Localization | Cell membrane; Lipid-anchor, GPI-anchor; Apical cell membrane; Cell surface; Localized to the apical glycocalyx surface |
| Species Reactivity | Human; Rat; Mouse |
Background
This gene encodes a protein that belongs to the carcinoembryonic antigen (CEA) family, whose members are glycosyl phosphatidyl inositol (GPI)-anchored cell surface glycoproteins. Members of this family play a role in cell adhesion and are widely used as tumor markers in serum immunoassay determinations of carcinoma.
This gene affects the sensitivity of tumor cells to adenovirus infection. The protein encoded by this gene acts as a receptor for adherent-invasive E. coli adhesion to the surface of ileal epithelial cells in patients with Crohn’s disease.
This gene is clustered with genes and pseudogenes of the cell adhesion molecules subgroup of the CEA family on chromosome 19. (provided by RefSeq, Apr 2014)
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