Thermo Fisher Scientific GGT5 light chain Polyclonal Antibody
Rabbit polyclonal antibody against human GGT5 light chain for ELISA and research use. Recognizes human, mouse, and rat. Protein A purified, liquid form, 1 mg/mL concentration. Stored at -20°C in PBS with glycerol and BSA.
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Applications
- ELISA (ELISA)
Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human Gamma-glutamyltransferase 5 light chain (amino acids 388–450) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with 50% glycerol, 1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Gamma-glutamyl transpeptidase (GGT) acts as a glutathionase and catalyzes the transfer of the glutamyl moiety of glutathione to various amino acids and dipeptide acceptors. This enzyme is located on the outer surface of the cell membrane and is widely distributed in mammalian tissues involved in absorption and secretion. In humans, hepatic GGT activity is elevated in certain liver diseases. GGT1 is released into the bloodstream after liver damage, and elevated levels may indicate hepatocellular carcinoma.
GGT5 converts Leukotriene C4 to Leukotriene D4 but does not convert synthetic substrates commonly used to assay GGT. In human serum and tissues, GGT heterogeneity is attributed to different glycosylation of the same peptide rather than different genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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