Thermo Fisher Scientific MMRN1 Polyclonal Antibody
MMRN1 단백질을 인식하는 Thermo Fisher Scientific의 rabbit polyclonal antibody로, WB 및 ICC/IF에 적합합니다. 고순도 항원 친화 크로마토그래피로 정제되었으며, 인간 및 마우스 반응성을 보입니다. 연구용으로 안정적인 단기 및 장기 보관이 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1083–1228 of human MMRN1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2720704 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. The purity is >95% (by SDS-PAGE).
Target Information
Multimerin-1 (MMRN1), also known as EMILIN-4 or ECM (endothelial cell multimerin), is a 1,228 amino acid secreted protein containing one C1q domain, one EMI domain, and one EGF-like domain. It is synthesized in megakaryocytes and endothelial cells and found in liver, lung, and placenta. Multimerin-1 forms a multimeric structure with disulfide-linked multimers and functions as a carrier protein for platelet factor V, aiding in its stabilization and storage in platelets. It also acts as a ligand for select integrins, contributing to extracellular matrix adhesion. Mutations causing Multimerin-1 deficiency are associated with autosomal dominant bleeding disorders due to platelet factor malfunction. Multiple isoforms exist due to alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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