
Thermo Fisher Scientific PD-L1 Monoclonal Antibody (OTI2C7), TrueMAB
PD-L1 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western blot, ICC/IF, Flow cytometry, ELISA 등 다양한 응용에 사용 가능. Human 시료 반응성, 고순도 정제, 안정한 액상 형태로 연구용에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:200–1:2,000 | - |
| Immunocytochemistry (ICC/IF) | 1:100 | - |
| Flow Cytometry (Flow) | Assay-dependent | - |
| ELISA | Assay-dependent | - |
| Luminex | Assay-dependent | - |
| Miscellaneous PubMed | - | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2C7 |
| Immunogen | Full-length human recombinant protein of human CD274 produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Programmed death receptor ligand 1 (PD-L1, also called B7-H1) is a B7 family member that binds to the programmed death receptor 1 (PD-1). This interaction negatively regulates T-cell receptor (TCR) signaling, reducing TCR-mediated proliferation and cytokine production. PD-L1 expression is abundant in many murine and human cancers and can be upregulated by IFN-gamma stimulation, suggesting a role in tumor immune evasion.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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