Thermo Fisher Scientific Separase Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

-

Immunocytochemistry (ICC/IF)

1:100-1:500

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human ESPL1(Accession Q14674), corresponding to amino acid residues F1100-L1150. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Separase,uniProtId:Q14674-1,ncbiNodeId:9606,antigenRange:1100-1150,antigenLength:2120,antigenImageFileName:PA5-99714_Separase_Q14674-1_Rabbit.svg,antigenImageFileNamePDP:PA5-99714_Separase_Q14674-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2818647

Product Specific Information

Antibody detects endogenous levels of total Separase.

Target Information

Caspase-like protease, which plays a central role in the chromosome segregation by cleaving the SCC1/RAD21 subunit of the cohesin complex at the onset of anaphase. During most of the cell cycle, it is inactivated by different mechanisms.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.