Thermo Fisher Scientific TRIM63 Monoclonal Antibody (6G6)

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:1,000

ELISA

• Tested Dilution: 1:500–1:1,000

Product Specifications

Product Specific Information

Sequence of this protein is as follows:
DKSTKLVETA IQSLDEPGGA TFLLTAKQLI KSIVEASKGC QLGKTEQGFE NMDFFTLDLE HIADALRAID FGTDEEEEEF IEEEDQEEEE STEGKEEGH

Target Information

This gene encodes a member of the RING zinc finger protein family found in striated muscle and iris.
The product of this gene is localized to the Z-line and M-line lattices of myofibrils, where titin’s N-terminal and C-terminal regions respectively bind to the sarcomere.
In vitro binding studies have shown that this protein also binds directly to titin near the region of titin containing kinase activity.
Another member of this protein family binds to microtubules, and since these family members can form heterodimers, this suggests that these proteins may serve as a link between titin kinase and microtubule-dependent signal pathways in muscle.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.