Thermo Fisher Scientific TRIM63 Monoclonal Antibody (6G6)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

ELISA (ELISA)

1:500-1:1,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

6G6

Immunogen

TRIM63 (NP_115977, 254 a.a. approximately 352 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:MURF1,uniProtId:Q969Q1-1,ncbiNodeId:9606,antigenRange:254-352,antigenLength:353,antigenImageFileName:H00084676-M01A_MURF1_Q969Q1-1_House_mouse.svg,antigenImageFileNamePDP:H00084676-M01A_MURF1_Q969Q1-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Storage buffer

ascites

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: DKSTKLVETA IQSLDEPGGA TFLLTAKQLI KSIVEASKGC QLGKTEQGFE NMDFFTLDLE HIADALRAID FGTDEEEEEF IEEEDQEEEE STEGKEEGH

Target Information

This gene encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is localized to the Z-line and M-line lattices of myofibrils, where titin`s N-terminal and C-terminal regions respectively bind to the sarcomere. In vitro binding studies have shown that this protein also binds directly to titin near the region of titin containing kinase activity. Another member of this protein family binds to microtubules. Since these family members can form heterodimers, this suggests that these proteins may serve as a link between titin kinase and microtubule-dependent signal pathways in muscle.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.