Thermo Fisher Scientific BIKE Polyclonal Antibody
BIKE 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot에 적합합니다. 인간, 생쥐, 랫트 시료에 반응하며, 고순도 친화 크로마토그래피로 정제되었습니다. PBS와 글리세롤 용액 형태로 제공되며, -20°C에서 보관합니다.
- 카탈로그번호
- PA5114911
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human BMP2K (Accession Q9NSY1), corresponding to amino acid residues S599–R649 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899547 |
Product Specific Information
Antibody detects endogenous levels of total BMP2K.
Target Information
The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis, and apoptosis.
A group of proteins intimately involved in this process are the serine/threonine (Ser/Thr) protein kinases.
BMP2K (BMP2 inducible kinase), also known as BIKE, is a 1,161 amino acid nuclear protein that contains one protein kinase domain and belongs to the Ser/Thr protein kinase family.
It is thought to be involved in osteoblast differentiation and catalyzes the ATP-dependent phosphorylation of bone morphogenic proteins (BMPs), which are essential for proper cartilage and bone formation.
Through its catalytic activity, BMP2K may play a role in signaling pathways that mediate bone growth and cellular differentiation.
Three isoforms of BMP2K exist due to alternative splicing events.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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