Thermo Fisher Scientific NMNAT1 Monoclonal Antibody (675112)
인간 NMNAT1 단백질을 인식하는 Mouse IgG2b 단일클론 항체. IHC(F)에서 8–25 µg/mL로 사용 가능. 단백질 A/G로 정제된 동결건조 제품으로, PBS(5% 트레할로스) 버퍼에 보관. NAD 생합성 연구용에 적합.
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Applications
- Immunohistochemistry (Frozen) (IHC (F)): 8–25 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 675112 |
| Immunogen | Sf21-derived recombinant human NMNAT-1 (Met1–Thr279) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.5 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2577229 |
Product Specific Information
Reconstitute in sterile PBS to a final concentration of 0.5 mg/mL.
Target Information
The coenzyme NAD and its derivatives are involved in hundreds of metabolic redox reactions and are utilized in protein ADP-ribosylation, histone deacetylation, and in some Ca(2+) signaling pathways.
NMNAT (EC 2.7.7.1) is a central enzyme in NAD biosynthesis, catalyzing the condensation of nicotinamide mononucleotide (NMN) or nicotinic acid mononucleotide (NaMN) with the AMP moiety of ATP to form NAD or NaAD.
(Zhang et al., 2003 [PubMed 12574164]). [Supplied by OMIM]
Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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