Thermo Fisher Scientific RHOBTB1 Polyclonal Antibody
RHOBTB1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC, ELISA 등 다양한 응용에 사용 가능. 고순도 Protein A 정제, 1 mg/mL 농도, -20°C 보관. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:100–1:500 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human RHOBTB1, amino acids 151–250 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
RHOBTB1 (Rho-related BTB domain-containing protein 1) and RHOBTB3 (Rho-related BTB domain-containing protein 3) each contain two BTB (POZ) domains and belong to the RhoBTB subfamily of Rho GTPases.
Members of this subfamily are evolutionarily conserved and characterized by a proline-rich region, a GTPase domain, and two tandem BTB repeats.
RHOBTB1 is highly expressed in placenta, stomach, testis, kidney, and skeletal muscle, while RHOBTB3 is abundant in neural and cardiac tissues.
RHOBTB1 may play a role in GTPase-mediated signaling and actin filament organization.
Decreased RHOBTB1 expression in head and neck carcinomas suggests a potential tumor suppressor function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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