Thermo Fisher Scientific Human ZMYM2 Synthetic Peptide
인간 ZMYM2 단백질의 아미노 말단 17개 아미노산 서열에 해당하는 합성 펩타이드입니다. PA5-21090 항체의 차단 펩타이드로 사용 가능하며, 인간 시료에 반응합니다. 액상 형태로 제공되며, PBS 버퍼(pH 7.2, 0.1% BSA)와 0.02% sodium azide를 포함합니다. 연구용으로만 사용되며, -20°C에서 보관합니다.
- 카탈로그번호
- PEP1204
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific Human ZMYM2 Synthetic Peptide
Applications
- Control (Ctrl): Assay-dependent
- Blocking Assay (BLOCK): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 17 amino acids near the amino terminus of human ZMYM2.
PEP-1204 can be used as a blocking peptide with polyclonal antibody PA5-21090.
Target Information
ZNF198 is a ubiquitously expressed nuclear protein whose physiological role is largely unknown.
It consists of five N-terminal zinc finger motifs responsible for protein-protein interactions, a central proline-rich domain, and a C-terminal nuclear localization signal (NLS) and acidic domain.
Reciprocal chromosomal translocation involving ZNF198 and FGFR1 results in the formation of ZNF198/FGFR1 fusion kinase protein. This fusion protein is a ligand-dependent, constitutively active cytoplasmic tyrosine kinase and regulates several STAT transcription factors including STAT1, STAT3, and STAT5.
This fusion protein is oncogenic and is associated with atypical myeloproliferative disease, peripheral blood eosinophilia, and T-cell leukemia/lymphoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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